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Artigos Científicos

Base Científica Sólida para Aplicações Clínicas

Base Científica para Campos Eletromagnéticos Pulsados, Luz Vermelha e Infravermelha

O PLR System® foi desenvolvido com fundamento em décadas de pesquisas internacionais sobre fotobiomodulação, terapia por luz vermelha e infravermelha, campos eletromagnéticos pulsados (PEMF) e estimulação biofísica de tecidos musculares, articulares, ósseos e cutâneos.

Diversos estudos publicados em periódicos médicos de alta relevância — incluindo PubMed, Nature, Journal of Photochemistry & Photobiology, Lasers in Medical Science e outras bases científicas — demonstram, de forma consistente, que:

  • PEMF promove modulação inflamatória, angiogênese e regeneração tecidual;
  • Estímulos fotoeletromagnéticos reduzem dor, edema e aceleram reparo;
  • A luz vermelha e infravermelha estimula a atividade mitocondrial e aumenta ATP;
  • Frequências específicas interagem com ritmos fisiológicos e processos celulares.

Embora cada estudo utilize metodologias e dispositivos distintos, todos reforçam os mecanismos biofísicos fundamentais incorporados ao PLR System, que combinam luz visível, infravermelho e campos eletromagnéticos pulsados de forma sinérgica.

A seguir, apresentamos uma seleção de artigos científicos, revisões sistemáticas e publicações internacionais que abordam os fundamentos biofísicos utilizados no PLR System.

Essas referências ajudam profissionais a compreenderem a base teórica, fisiológica e experimental por trás da tecnologia.

Artigos Científicos Selecionados

  1. Effects of transcranial direct current stimulation on working memory in patients with Parkinson’s disease
  2. Effects of low-power light therapy on wound healing: LASER x LED
  3. Electromagnetic effects – From cell biology to medicine
  4. Low frequency pulsed electromagnetic field – A viable alternative therapy for arthritis
  5. Cellular target of weak magnetic fields: ionic conduction along actin filaments of microvilli
  6. Randomized, Double-Blind, and Placebo-Controlled Clinic Report of Intranasal Low-Intensity Laser Therapy on Vascular Diseases
  7. Effect of Pulsing in Low-Level Light Therapy
  8. Biphasic Dose Response in Low Level Light Therapy
  9. Primary and secondary mechanisms of action of visible to near-IR radiation on cells
  10. Exact Action Spectra for Cellular Responses Relevant to Phototherapy
  11. Transcranial magnetic stimulation (TMS)/repetitive TMS in mild cognitive impairment and Alzheimer’s disease
  12. Headache Treatment with Pulsing Electromagnetic Fields: A Literature Review
  13. Effect of NASA Light-Emitting Diode Irradiation on Wound Healing
  14. Osteogenic differentiation of amniotic epithelial cells: synergism of pulsed electromagnetic field and biochemical stimuli
  15. Effects of pulsed electromagnetic fields on patients’ recovery after arthroscopic surgery: prospective, randomized and double-blind study
  16. Low-Level Laser (Light) Therapy (LLLT) in Skin: Stimulating, Healing, Restoring
  17. Acceleration of Fracture Repair by Electromagnetic Fields. A Surgically Noninvasive Method
  18. Long-Term Pulsed Electromagnetic Field (PEMF) Results in Congenital Pseudarthrosis
  19. Pulsed electromagnetic field (PEMF) treatment for fracture healing
  20. Light-emitting diode phototherapy improves muscle recovery after a damaging exercise
  21. Exposure to Low Frequency Pulsed Electromagnetic Fields Increases Interleukin-1 and Interleukin-6 Production by Human Peripheral Blood Mononuclear Cells
  22. Light-emitting diode therapy (LEDT) before matches prevents increase in creatine kinase with a light dose response in volleyball players
  23. Time response of increases in ATP and muscle resistance to fatigue after low-level laser (light) therapy (LLLT) in mice
  24. In vitro functional response of human tendon cells to different dosages of low-frequency pulsed electromagnetic field
  25. Mechanisms of Low Level Light Therapy
  26. Effect of near-infrared light-emitting diodes on nerve regeneration
  27. Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis
  28. Adjunctive use of combination of super-pulsed laser and light-emitting diodes phototherapy on nonspecific knee pain: double-blinded randomized placebo-controlled trial
  29. Effect of Cluster Multi-Diode Light Emitting Diode Therapy (LEDT) on Exercise-Induced Skeletal Muscle Fatigue and Skeletal Muscle Recovery in Humans
  30. Pulsed Electromagnetic Fields Reduce Postoperative Interleukin-1β, Pain, and Inflammation: A DoubleBlind, Placebo-Controlled Study in TRAM Flap Breast Reconstruction Patients
  31. Formation of Gigantic Mitochondria In Human Blood Lymphocytes Under the Effect of a He Ne Laser
  32. Neurological and psychological applications of transcranial lasers and LEDs
  33. Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial
  34. Improvements in Gulf War Illness Symptoms After Near-Infrared Transcranial and Intranasal Photobiomodulation: Two Case Reports
  35. How photons modulate wound healing via the immune system
  36. Improvements in clinical signs of Parkinson’s disease using photobiomodulation: A prospective proof-of-concept study
  37. Intravenous Laser Irradiation of Blood: current state and future perspectives
  38. Monte Carlo analysis of the enhanced transcranial penetration using distributed near-infrared emitter array
  39. Fotomedicina Básica
  40. Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report
  41. The nuts and bolts of low-level laser (light) therapy
  42. Therapeutic photobiomodulation: nitric oxide and a novel function of mitochondrial cytochrome c oxidase
  43. Transcranial photobiomodulation with near-infrared light from childhood to elderliness: simulation of dosimetry

A Ciência como Base para a Prática Clínica Moderna

A eficácia de terapias baseadas em luz e campos eletromagnéticos é amplamente documentada na literatura médica. O PLR System foi projetado seguindo esses princípios, integrando tecnologia avançada com parâmetros biofisiológicos consistentes, permitindo que profissionais de saúde ofereçam:

  • Tratamentos seguros;
  • Resultados mensuráveis;
  • Intervenções não invasivas;
  • Aplicações versáteis em diferentes especialidades.

Profissionais podem, portanto, contar com um dispositivo respaldado nos mecanismos mais estudados e aceitos da bioestimulação moderna, além dos resultados já observados em casos de uso com o PLR System.